Introduction: Juvenile nasopharyngeal angiofibroma is a rare, highly .. Luiz A CR, Romualdo S LT, Fava A S. Angiofibroma nasofaríngeo: revisão de literatura. Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor arising predominantly in the nasopharynx of adolescent males. It is an aggressive. Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas.

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Figure 7 shows mast cells in toluidine blue stain. Noradrenergic innervation of juvenile nasopharyngeal angiofibroma.

Nasopharyngeal angiofibroma: Our experience and literature review

Transcatheter arterial embolization in nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibromas present almost exclusively in men aged 14—25 years 23 24 25 26 27 These tumors occur almost exclusively in male adolescents and account for 0. Therefore there is need for further action to claim that this technique has a low recurrence rate, since the recurrence is probably related to incomplete resection of the initial tumor.

Removal is important in preventing nasal obstruction and angifoibroma epistaxis. Article accepted in April 21, Universidade Federal de Sergipe. Retrospective, descriptive study conducted after approval from the Ethics Committee of the Federal University of Sergipe protocol Nasopharyngeal angiofibroma[TI] free full text[sb]. Computed tomography of a year-old patient with a Fisch class IIIa juvenile nasopharyngeal angiofibroma.

Article accepted in October 7, Nasofarinyeo five patients in this study underwent endoscopic resection four days after arteriography with embolization. Tumors may invade the anterior fossa through the ethmoid and sphenoid sinuses, being more frequent in the middle fossa and remaining extradural 8 9 A biopsy is recommended only in cases of diagnostic uncertainty4.


Endoscopic Surgery of Nasopharyngeal Angiofibroma

Epistaxis, rhinorrhea and pain may also be seen. Arch Pathol Lab Med. Case 4 Case 4.

MANN et al 21 in a retrospective study found a recurrence rate of 6. This page was last edited on 29 Septemberjasofaringeo In addition, the releasing inhibition and function of these growing factors is a nzsofaringeo therapeutic target for certain cases of JNA A concise classification system and appropriate treatment options.

The encounter of two copies of AR gene in JNA cells cores, along with the presence of AR, remarks the importance of androgen stimulation in this tumor pathogenesis.

Surgical excision was done with moderate intraoperative bleeding. When diagnosed early the patients are treated with a combination of preoperative embolization and surgical resection providing a good prognosis.

More recently some authors have reported endoscopic resection in stages I through IIIA Radkowski be demonstrated to be safe, effective, decrease blood loss during anfiofibroma, as well as lower rates of complications, hospitalization time and rate of tumor recurrence, especially in tumors without intracranial extension 9,17,22, CT of the paranasal sinuses.

Other methods such as hormone therapy, radiotherapy and chemotherapy treatment modalities are now used occasionally as complementary treatments 9,14,16,17, The final diagnosis is achieved by histopathologic examination of tissue sections either on incisional or excisional biopsy.


Endoscopic Surgery for Juvenile Angiofibroma: See staging of juvenile nasopharyngeal angiofibromas. It shows very aggressive behavior due to local invasiveness and is associated with various symptoms. Definitive Radiotherapy for Juvenile Nasopharyngeal Angiofibroma. Tumor size was not associated with bleeding.

Ulcerations are commonly found in the JNA periphery, angiofirboma vascularization is more intense and is poor in terms of fibrous stroma. Intracranial juvenile nasopharyngeal angiofibroma. However, most authors agree that JNAs arise from the posterior choanal tissues in the region of the sphenopalatine foramen. Mesothelioma Malignant solitary fibrous tumor. Angiography, although not essential, is often useful in both defining the feeding vessels as well as in preoperative embolisation.

Exclusively endoscopic removal of juvenile nasopharyngeal angiofibroma: Aromatase may play a critical role in the pathogenesis of juvenile nasopharyngeal angiofibroma. Vascularization arises most frequently from the maxillary artery i.

Preoperative embolisation of tumour may be of some use in reducing intraoperative bleeding. How to cite this article. However, no changes are found in the sexual hormones serum levels 39,42 nor changes in the JNA patients sexual maturity.

It impinges nasofringeo adjacent structures and causes pressure erosion of bone.